{"id":2414,"date":"2025-04-03T15:08:14","date_gmt":"2025-04-03T13:08:14","guid":{"rendered":"https:\/\/chemspx.com\/instruments\/phoenix-dry-heat-diffusion-cells\/"},"modified":"2025-04-17T13:45:26","modified_gmt":"2025-04-17T11:45:26","slug":"phoenix-dry-heat-diffusion-cells","status":"publish","type":"instruments","link":"https:\/\/chemspx.com\/fr\/instruments\/phoenix-dry-heat-diffusion-cells\/","title":{"rendered":"Phoenix Dry Heat Diffusion Cells"},"content":{"rendered":"

The Phoenix\u2122 Dry Heat Diffusion Cell offers improved ease of use, high durability, and greater versatility as compared to conventional hand-blown vertical diffusion cells. In addition, Phoenix cells operate on dry heat; no water-jacketing is required. This allows construction from heavy-duty borosilicate glass, held to very tight dimensional tolerances. Moreover, the extract-and-replace sampling through the large diameter opening in the sampling arm accommodates standard pipette tips (~300 \u03bcL). This simplifies the sampling process while reducing training and operating costs.<\/span><\/p>\n

 <\/p>\n

Powerful Mixing<\/strong><\/span><\/p>\n

Special grooves machined into the tops and sides of the mixer-inserts provide strong circulation and nearly instantaneous homogenization of cell contents. This system prevents the formation of regions of higher concentration of API under the membrane, thereby reducing test variability. This ensures the accuracy and consistency needed for permeability testing.<\/p>\n

\u200b<\/p>\n

Test Preparation<\/strong><\/span><\/h3>\n

Phoenix cells are quick to set up. Dosage forms are applied to an easily accessible opening in the cell cap. No clamps are required. Bubbles are easily detected and removed simply by lifting the cell and tipping it to one side. This ease of use simplifies the setup for permeability testing, making the process more efficient.<\/p>\n

 <\/p>\n

Chemical Compatibility<\/strong><\/span><\/h3>\n

The Phoenix press-on style of cell cap is made from polyether ether ketone (PEEK), sealed with O\u2011rings made from Viton\u2122 (fluor elastomer). The Phoenix threaded style of cell cap is made from polytetrafluoroethylene (PTFE). It is sealed with O-rings made from either Viton or Kalrez\u2122 (perfluoro elastomer). This provides higher compatibility with aggressive solvents such as THF and DMSO.<\/p>\n

 <\/p>\n

\n

Diffusion Cell Design<\/strong><\/span><\/h3>\n<\/div>\n
\n
\n

The most critical aspect of any lab testing instrument is its ability to produce results that are both accurate and precise. In other words, accuracy ensures true results, while precision ensures consistency from one test to the next. However, variability\u2014the enemy of precision\u2014comes from inconsistencies in the test instrument itself, the test procedure, and the materials being tested.<\/p>\n

With these factors in mind, the Phoenix dry heat diffusion cell is designed to eliminate instrument variability. It significantly reduces the potential for procedural inconsistencies (operator error). By incorporating improvements based on 30 years of experience in manual and automated diffusion cell systems, the Phoenix cell is more durable and easier to operate. This, it also provides significantly better test results.<\/p>\n

Constructed of precision-bore tubing such as found in barrel syringes, each borosilicate glass cell is dimensionally consistent with the next. The generous 9 mm internal diameter of the sampling arm promotes rapid homogenization of receptor media. It allows the use of standard pipette tips to save on costs. Standard 16 mm evaporation caps fit onto the flanged end of the sampling arm.<\/p>\n

    \n
  • Phoenix cells are durable, portable, quick to assemble, and easy to clean.<\/li>\n
  • Three different styles of cell cap kits are designed to work interchangeably with each cell.<\/li>\n
  • Slotted evaporation caps prevent loss of media while allowing manual sampling by pipette or auto sampling by probe.<\/li>\n
  • Fill mark conveniently indicates receptor media has reached the level of the membrane.<\/li>\n<\/ul>\n<\/div>\n

     <\/p>\n

    Receptor Media Volume Adjustment<\/strong><\/span><\/h3>\n

    \"\"Phoenix diffusion cells allow the analyst to adjust receptor media volume simply by changing the mixer-insert. For instance, the use of the short mixer-insert (13 mm height) provides the maximum available volume for a particular cell size. The tall mixer insert (30 mm height) provides a lesser volume while still allowing samples to be taken from the centre of the main body of the cell as specified in USP <1724> Semisolid Drug Products\u2014Performance Tests. This flexibility is especially beneficial when conducting permeability testing, as it allows for precise control over the test conditions.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

    Designed for precision, versatility, and ease\u2010of\u2010use in diffusion\u2010testing labs<\/p>\n","protected":false},"featured_media":2999,"template":"","country":[650,649],"brands":[635],"applications":[638,570],"markets":[14,25,24],"acf":[],"yoast_head":"\nPhoenix Dry Heat Diffusion Cells - ChemSPX<\/title>\n<meta name=\"description\" content=\"The Phoenix\u2122 Dry Heat Diffusion Cell simplifies permeability testing with dry heat, efficient mixing, and easy sampling for accurate results.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/chemspx.com\/fr\/instruments\/phoenix-dry-heat-diffusion-cells\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Phoenix Dry Heat Diffusion Cells - ChemSPX\" \/>\n<meta property=\"og:description\" content=\"The Phoenix\u2122 Dry Heat Diffusion Cell simplifies permeability testing with dry heat, efficient mixing, and easy sampling for accurate results.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/chemspx.com\/fr\/instruments\/phoenix-dry-heat-diffusion-cells\/\" \/>\n<meta property=\"og:site_name\" content=\"ChemSPX\" \/>\n<meta property=\"article:modified_time\" content=\"2025-04-17T11:45:26+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/chemspx.com\/wp-content\/uploads\/2023\/01\/Phoenix-Cells-Press-on-Three-Sizes-2649x1701px-1024x658-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"658\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/chemspx.com\/fr\/instruments\/phoenix-dry-heat-diffusion-cells\/\",\"url\":\"https:\/\/chemspx.com\/fr\/instruments\/phoenix-dry-heat-diffusion-cells\/\",\"name\":\"Phoenix Dry Heat Diffusion Cells - 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