Atlas HD Modular Jacketed Reactor

Modular jacketed reactor system for process development

The Atlas HD family is a modular and automated jacketed reactor platform designed for a wide range of laboratory applications. The system offers seamless interchangeability of jacketed reactors from 50 mL to 5 L, allowing laboratories to configure a single platform for different reaction volumes and processes.

Used extensively by process development groups worldwide, Atlas HD combines automated process control, integrated safety features, recipe management and real-time reaction monitoring to support reliable and reproducible chemistry.

Automated control for reproducible reactions

Atlas HD provides precise control over key reaction parameters, helping chemists achieve consistent experimental conditions.

The system offers:

• Temperature control from -90 °C to +250 °C
• Automated stirring control
• Real-time reaction monitoring and graphing
• Built-in safety protocols for unattended (“walk-away”) chemistry
• Full recipe control for automated experiments

A range of sensors, including temperature, pressure, pH and turbidity, can be integrated into the system. Automated dosing is also supported through the Atlas Syringe Pump, allowing reactions and reagent addition to continue under controlled conditions even when the operator is away from the laboratory.

Flexible automation options

Atlas HD can be operated directly from the integrated touchscreen on the Atlas HD Base.

The touchscreen enables users to:

• Program complex multi-step experiments
• Create dosing profiles, including pH- and temperature-controlled dosing
• Configure safety shutdown protocols
• Run and monitor automated reactions

Designed with an intuitive interface similar to a smartphone application, the touchscreen allows both new and experienced users to define, monitor and control experiments without extensive training.

For more advanced applications, Atlas PC Software provides additional automation capabilities.

The software allows users to:

• Configure and analyze experiments
• Create, modify and save complex reaction recipes using a drag-and-drop interface
• Control Atlas HD together with virtually any manufacturer’s RS232-enabled laboratory equipment, including stirrer motors, circulators, pumps, balances and RTDs

Designed for daily laboratory use

Atlas HD combines robust construction with practical design features to support routine laboratory operation.

Features include:

• Quick-clamp system for fast vessel removal and cleaning
• Quick-release Scorpion Motor for simple installation and removal
• High-quality borosilicate glassware manufactured and tested by Syrris chemists and chemical engineers
• Availability of custom glassware and components, including vessels, stirrers and condensers

Flexible platform for multiple applications

Thanks to its modular design, Atlas HD can be configured for a variety of applications while using the same reactor platform.

Supported applications include:

• Process development
• Advanced synthesis
• Process optimization
• Polymerization
• Crystallization and sonocrystallization
• Reaction calorimetry
• High-pressure reactions
• Chemistry in flasks and vials

The system also supports straightforward scale-up through interchangeable handmade borosilicate glass jacketed vessels ranging from 50 mL to 5 L.

What is a jacketed reactor?

A jacketed reactor is a glass or stainless steel reaction vessel that controls the temperature of the reaction using a surrounding jacket filled with heating or cooling fluid.

Unlike traditional round-bottom flasks, which are typically limited to a small number of fixed operating temperatures, a jacketed reactor connected to a circulator provides accurate temperature control across the required operating range. This allows reactions to be performed under precisely controlled thermal conditions.

Key features

• Modular jacketed reactor platform for 50 mL to 5 L vessels
• Automated control of temperature, stirring and dosing
• Operating temperature range from -90 °C to +250 °C
• Real-time monitoring, graphing and recipe management
• Built-in safety protocols for unattended operation
• Touchscreen control with optional Atlas PC Software
• Compatible with RS232-enabled laboratory equipment
• Supports sensors for temperature, pressure, pH and turbidity
• Quick-clamp vessel system and quick-release motor
• Configurable for reaction calorimetry, crystallization, pressure chemistry, polymerization and advanced synthesis
• Custom glassware and reactor components available

Application-specific configurations

Atlas HD can be configured for several specialized applications:

Advanced synthesis

The platform supports complex synthesis workflows involving multiple dosing profiles and Process Analytical Technology (PAT) feedback. It can operate across a wide temperature range, from cryogenic conditions to high-temperature reactions.

Reaction calorimetry

The Atlas HD Reaction Calorimeter supports both Heat Flow Calorimetry (HFC) and Power Compensation Calorimetry (PCC), helping users study the thermal behavior and potential hazards of chemical reactions.

Crystallization

The Atlas HD Crystallization Reactor automatically controls temperature and reagent dosing during crystallization while monitoring crystal growth using a turbidity probe.

Ultrasound technology enables reproducible crystallization and allows control over properties such as:

• Particle size
• Particle shape
• Crystallinity
• Polymorphism

Pressure reactions

The Atlas HD 3 Bar Pressure System is designed for reactions requiring elevated pressure or high vacuum, including applications such as hydrogenation and carbonylation.

Technical specifications