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Four-zone reaction station for automated heating, cooling and reaction control
The Mya 4 Reaction Station is a four-zone reaction platform designed for safe and precise heating, active cooling, software-controlled operation and data logging. With independently controlled reaction zones, it enables unattended 24/7 chemistry while supporting multiple experiments or users on a single compact system.
The system is suitable for a wide range of research and process development applications, including:
- Process development
- Design of Experiments (DoE)
- Scale-up studies
- Route scouting
- Polymorph screening
- Biopharmaceutical research
- Reaction optimization
- Lead optimization
- Crystallization studies
- Reagent, catalyst and solvent screening
Independent temperature control
Each of the four reaction zones can be controlled independently, allowing different experiments to run simultaneously. The station offers a block temperature range from -30 °C to +180 °C, providing solution temperatures of at least –20 °C to +150 °C.
Users can choose to control temperature based on either the heating block or the reaction solution. High-performance insulation minimizes heat transfer between adjacent zones, allowing temperature differences of up to 200 °C between neighboring positions. This makes the system well suited for multi-user operation or multiple projects running in parallel.
Powerful Peltier technology provides active cooling, allowing temperatures down to -25 °C using tap water without requiring a separate chiller.
Cooling performance depends on the water source used:
| Peltier cooling source | Tap water at 15 °C | Chilled water at 5 °C |
|---|---|---|
| Minimum block temperature (internal probe) | −25 °C | −20 °C |
| Minimum solution temperature (external probe) | −30 °C | −25 °C |
Flexible vessel compatibility
The Mya 4 accommodates a wide variety of reaction vessels ranging from 2 to 400 mL, making it suitable for both small-scale screening and larger process development experiments.
Compatible vessels include:
- Vials and tubes from 2 to 20 mL
- Round-bottom flasks from 25 to 250 mL (Carousel 6 Plus range)
- Process reaction vessels from 50 to 400 mL
- Three- or five-neck glass lids for process vessels
Magnetic or optional overhead stirring
Integrated magnetic stirring is supplied as standard, with independent control for each reaction position from 100 to 1000 rpm.
For applications requiring mechanical stirring, the optional Mya Compact Stirrer provides powerful, high-torque overhead stirring with tool-free attachment. Magnetic stirring and overhead stirring can be used simultaneously in adjacent reaction zones, with each position controlled independently.
Manifold head or reflux head
The Mya 4 can be configured with either a manifold head or a reflux head, depending on the application.
- The manifold head distributes cooling water to individual glass condensers and incorporates non-return shut-off valves.
- The water-cooled reflux head provides efficient reflux by cooling the outside of the reflux tubes. It also enables the distribution of inert gas for reactions requiring an inert atmosphere.
Software control and data logging
The system is supplied with an intuitive touchscreen control pad that supports both manual operation and automated temperature profiles. Experimental profiles can be repeated, while reaction data can be exported in CSV format.
Optional PC Control Software expands the system by allowing integration and control of compatible third-party devices, including pumps, balances and pH sensors.
Compact design for individual or shared use
Despite offering four independently controlled reaction zones, the Mya 4 occupies less bench space than four separate reaction setups. Excellent visibility of the reaction vessels allows experiments to be monitored easily, while the independent control of heating, cooling and stirring makes the system suitable for both individual researchers and shared laboratory environments.
Key features
- Four independently controlled reaction zones
- Suitable for unattended 24/7 operation
- Block temperature range from -30 °C to +180 °C
- Solution temperature range of at least -20 °C to +150 °C
- Independent block or solution temperature control
- Up to 200 °C temperature difference between adjacent zones
- Active Peltier cooling to -25 °C using tap water without a separate chiller
- Integrated magnetic stirring from 100 to 1000 rpm
- Optional Mya Compact Stirrer for high-torque overhead stirring from 100 to 1000 rpm
- Independent stirring control for every reaction position
- Compatible with vessels from 2 to 400 mL
- Choice of water-cooled reflux head or manifold head
- Standard touchscreen control pad with optional PC software for automation, third-party device integration and data logging
- Compact benchtop design suitable for single-user or multi-user operation
