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Phoenix Flow Reactor

A versatile and safe continuous flow reactor for high-pressure, high-temperature chemistry
Temperature up to 450°C
Pressure up to 200 bar
Homogeneous and heterogeneous chemistry support

Phoenix Flow Reactor

Flow reactor for high-temperature, high-pressure reactions

The Phoenix™ Flow Reactor is designed for chemical reactions under extreme conditions, enabling synthesis in a parameter range that cannot easily be achieved with conventional laboratory equipment. With operation up to 450°C and 200 bar, the system expands the accessible reaction space for both homogeneous and heterogeneous chemistry applications.

By combining these operating conditions with the advantages of flow chemistry, the Phoenix™ platform enables safer and more controlled chemical processing.

Extended chemical parameter window 

One of the main advantages of the Phoenix™ Flow Reactor is its extended operating window. The system supports:

  • Temperatures up to 450°C
  • Pressures up to 200 bar
  • Homogeneous and heterogeneous reactions
  • High-temperature and high-pressure workflows

This broad operating range provides greater flexibility for reaction development and process optimization.

Supports both homogeneous and heterogeneous chemistry

The Phoenix™ platform is designed to accommodate multiple reaction types within a single system. For homogeneous chemistry, different reactor coil materials and volumes are available. For heterogeneous applications, dedicated cartridge-based reactor options can be used.

Available reactor options include:

  • PTFE coil reactors
  • Hastelloy coil reactors
  • Stainless-steel coil reactors
  • User-fillable metal-metal sealed cartridges
  • Prefilled CatCarts™
  • MidiCarts™

These options support catalyst testing and different reaction configurations without requiring major system modifications.

Simple interchange of reactors 

The system allows simple interchange of reactor elements, making it possible to adapt the setup for different applications.

Its modular architecture also enables integration with additional instruments and modules. This allows users to customize the system according to workflow requirements and expand functionality over time.

Additional modules and automation options can create a more comprehensive reaction platform.

Software and system control

The Phoenix™ Flow Reactor includes a user-friendly software interface with a movable GUI touchscreen, allowing flexible positioning and operation.

Control features include:

  • Real-time monitoring of reactor parameters
  • Touchscreen operation
  • Optional PC control
  • Intuitive setup and operation
  • Connection of multiple pumps and Gas Modules™

The updated interface improves usability and enables centralized control of connected components.

Rapid heating and controlled cooling

The system is designed for fast thermal response.

Features include:

  • Rapid heating to target temperatures
  • Cooling functionality for fast cooldown after reactions
  • Built-in fan for accelerated cooling
  • Controlled temperature regulation

The second-generation platform improves temperature management and eliminates overshoot behavior for more precise thermal control.

Multiple temperature monitoring points

Temperature can be monitored throughout the system using internal and optional external sensors.

This provides:

  • Monitoring at multiple locations
  • Improved thermal tracking
  • More reliable process information

Phoenix II Flow Reactor

The second-generation Phoenix II Flow Reactor™ builds on the original platform while maintaining its key characteristics, including the extended chemical parameter range and support for both homogeneous and heterogeneous reactions.

Improvements introduced in the updated system include:

  • More precise temperature regulation
  • Elimination of temperature overshoot
  • Faster cooldown performance
  • Improved setup and handling
  • Additional automation possibilities
  • Easier module integration

Key platform features

  • Temperature up to 450°C
  • Pressure up to 200 bar
  • Homogeneous and heterogeneous chemistry support
  • Multiple reactor options available
  • Rapid heating and cooling
  • Modular system design
  • Movable touchscreen interface
  • Optional PC control
  • Multiple temperature sensors
  • Automation capability
  • Connection of multiple pumps and Gas Modules™
  • Simple reactor exchange

This combination of high operating limits, modularity, and reactor flexibility makes the Phoenix™ Flow Reactor suitable for a broad range of flow chemistry applications.

Applications 

Basic configuration:

  • SNAr reactions
  • Boc-removal
  • Claisen rearrangement
  • C-alkylation
  • N-alkylation
  • Supercritical reactions
  • Heterocycle synthesis
  • Etc.

Addition to basic configuration:

  • Hydrogenation
  • Oxidation
  • Carbonylation
  • Etc.

Specifications 

Maximum temperature 450 °C
Warm‑up time 10 min (from 30 °C to 450 °C)
Maximum inlet pressure 200 bar (2900 psi)
Recommended environment Ventilated laboratory fume hood
Dimensions (H × W × D) 430 × 253 × 460 mm
Weight 25 kg
Power requirements 115 V or 235 V AC, 50–60 Hz
Power consumption 1500 + 1400 VA

 

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Le H-Genie® combined with the Phoenix Flow Reactor™ is an all-in-one flow chemistry system for catalyst testing, synthesis, optimization, and scale-up, useable in any laboratory fume hood.

This setup offers provides a wide temperature and pressure range along with high-pressure hydrogen safely generated without cylinders. It enables the synthesis from milligrams to kilograms on a single system, eliminating the need for costly infrastructure or additional equipment.

 

 

Questions about your application?

Our Xperts are happy to answer your questions and provide additional information about this instrument and its applications.

Frequently asked questions

Yes. With the help of as many Gas Modules™ as necessary and applying the Pressure Module™, it is possible to perform catalytic reactions in gas phase at high temperatures and pressures.

Both homogeneous and heterogeneous reactions, including SNAr reactions, protecting group removals, rearrangement reactions, alkylation, supercritical reactions, etc. Read our application notes and related publications for more information.

The Phoenix™ Flow Reactor is a high‑performance flow chemistry system designed to carry out chemical reactions under extreme conditions. It enables operation at temperatures up to 450 °C and pressures up to 200 bar, allowing reactions that are not easily achievable with conventional batch laboratory equipment.
The key difference is its ability to operate at very high temperature and pressure conditions while maintaining the advantages of flow chemistry. This allows safer, more controlled reactions and opens up a broader reaction parameter space compared to standard batch systems.
The system supports both homogeneous and heterogeneous chemistry. It can handle a wide range of reaction types, including reactions in solution as well as reactions using solid catalysts in packed cartridges.
The Phoenix™ Flow Reactor combines extreme operating conditions, modular design, flexible reactor configurations, and precise control. This makes it a powerful tool for reaction development, process optimization, and advanced flow chemistry research.

Downloads

Brochure Phoenix Flow Reactor II

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