H-Cube Mini plus

Flow reactor with on-demand hydrogen generation

The H-Cube^® Mini Plus is a safe, powerful and affordable flow reactor with on-demand hydrogen generation that generates high-pressure hydrogen via water electrolysis. This enables chemists to perform catalytic hydrogenations from atmospheric pressure and room temperature to 100 bar and 100 °C in minutes.

Extend your chemical synthesis capabilities 

Safety and convenience for hydrogenation 

Hydrogenation is one of the most important reactions in chemical synthesis, yet the hazardous nature of hydrogen limits its use. he H-Cube® series overcomes these risks through in situ hydrogen generation and the safe handling of pyrophoric catalysts in sealed catalyst cartridges (CatCarts®). This innovative technology has been widely adopted by leading organizations in the pharmaceutical, flavor and fragrance, fine chemical, and agrochemical industries, as well as in academia.

As a versatile flow reactor, the hydrogen generation system of the H-Cube^® Mini Plus can be easily turned off to allow non-hydrogenation reactions to be performed as well, such as C-C coupling reactions.

Features of the flow reactor with on-demand hydrogen generation 

• Hydrogenation without cylinders
• No catalyst filtration
• Fast reactions
• Easy-to-use
• Affordable
• Built-in video tutorial
• Automated hydrogen drying system

Applications 

Reactions with hydrogen gas:

Triple bond full reduction, debenzylation, nitrile reduction, selective nitro reduction, selective triple to double bond reduction, selective double bond reduction, aldose reduction, aromatic heterocycle reduction, aromatic ring reduction, etc.

Other reactions:

Deuteration, Sonogashira coupling, Suzuki coupling, etc.