PurIon

PurIon Mass Spec for Flash and Prep Labs

The PurIon™ Mass Spectrometer is provides highly affordable mass-directed fractionation for labs performing flash and prep purifications on Teledyne ISCO systems. The PurIon interfaces seamlessly with the CombiFlash® NextGen, CombiFlash® EZ Prep, and ACCQPrep® to instantly verify the identity of target compounds. Furthermore, the innovative PeakTrak® software provides single point of control, three predetermined ionization settings, and the ability to customize ionization parameters to maximize signal strength. Additionally, the Ion Finder utility helps identify fragments and adducts of your compound and optimize detection parameters from directly injected samples before purification. Highly accessible and easy-to-use, PurIon is ideal for chemists wanting high-quality mass spectral data without the need for specialized training.

Single Quadrupole Mass Analyzer

The PurIon is a compact, single-quadrupole mass analyzer with an atmospheric pressure interface, optimizing chromatography purification. Thus, it provides highly reliable molecular weight information about target compounds as well as other adducts during the purification run—or by direct-injection analysis prior to purification—in positive ion mode via proton attachment (M+H)+ and negative ion mode via proton removal (M-H)-

Versatile and Reliable

Co-eluting peaks isolate easily using mass selectivity based on mass-to-charge ratio (m/z) of the target analyte. Moreover, with electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) capabilities, PurIon delivers rapid and reliable confirmation of compounds. Whether working with normal-phase or reverse-phase applications, PurIon delivers consistent results. Its extended mass range, from 10 Da to 2000 Da, allows the detection of both small and large molecules.

Models 

“S” Model

The “S” Model has an operation range of 10 to 1,200 Da (m/z). For instance, the unit can be fitted with either an ESI or APCI ion source. These sources can be quickly exchanged in response to different application needs. Unlike the Base Model, the “S” Model automatically switches between positive and negative ionization modes throughout the run. Additionally, a fluid interface module is included with the PurIon Mass Spectrometer to remove miniscule sample from the purification flow stream and redirect this portion to the mass spectrometer for analysis.

“L” Model

The L Model has an operation range of 10 to 2,000 Da (m/z). The unit can be fitted with either an ESI or APCI ion source. These sources can be quickly exchanged in response to different application needs. Like the “S” Model, the “L” Model automatically switches between positive and negative ionization modes throughout the run. A fluid interface module is included with the PurIon Mass Spectrometer to remove miniscule sample from the purification flow stream and redirect this portion to the mass spectrometer for analysis.

No more TLC plates for flash. Really?

Yes, really, with the Focused Gradient Generator for flash. Read the info here.