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Teledyne Isco

CombiFlash Torrent

One liter per minute flow rates rapidly purify up to 300 grams of sample

CombiFlash Torrent

Large-scale Flash Purification

The CombiFlash Torrent is a large-scale flash purification system that delivers the same ease of use and reliability as the CombiFlash and RediSep® product lines. Designed for development-scale applications, it offers rapid purification with flow rates of up to one liter per minute and can purify up to 300 grams of sample.

Its 100 psi pumps deliver a precise and reproducible binary gradient. The CombiFlash Torrent system is built for flexibility, supporting a range of sample introduction and collection methods to meet diverse large-scale purification needs.

The reliable RediSep® columns​ use RFID technology to quickly generate error-free methods. Each column’s RFID tag allows for easy access to column information and method recall. Large-scale RediSep columns with quick Luer connections are available in various sizes and media types to suit different applications.

Safety

The patented active solvent sensing technology continuously monitors solvent supply and waste levels, enabling true walk-away automation. Built-in pressure and vapor sensors enhance safety by halting purification in case of overpressure or leaks. Fully grounded tubing ensures safe operation at high flow rates, while optional air purging of the column streamlines post-run disposal.

Versatility

Customize your system with a range of sample introduction and fraction handling configurations to suit your specific needs.

Highly Programmable and Easy to Use

ISCO’s PeakTrak software, the industry standard in flash chromatography, offers a powerful yet intuitive interface, allowing you to quickly access and edit all method parameters from a single screen.

Standard features of the large-scale flash purification system 

  • Run up to 1 L/min binary gradient system
  • 100 psi rated
  • Load up to 300 grams in a single purification run
  • Patented solvent and waste level sensing technology
  • Fully-grounded fluid path
  • Easy-to-use PeakTrak® software
  • Accepts RediSep column sizes from 80 g to 3 kg silica
  • RFID column detection
  • Automated six-port valve and large diameter tubing​​​

Related instruments

RediSep Flash Columns

Easy purification and scale-up from milligram to kilogram.

CombiFlash NextGen 300+

The CombiFlash NextGen 300+ comes standard with all options installed. Flow rate range is from 1 to 300 mL/min at operating pressures up to 300 psi (20 bar).

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