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Robotic Diffusion Station
The Phoenix RDS (Robotic Diffusion Station) is designed for fully automated sampling, collection, and aliquot replacement in vertical diffusion testing workflows. The system supports either six or twelve vertical diffusion cells within a compact footprint and uses the same heating and stirring blocks found in the DB-6 platform. Its flexible configuration allows adaptation to different receptor and dosage chamber volumes, orifice diameters, dosage forms, and membrane types.
Controlled through Diffusion Master™ software, up to two Phoenix RDS systems can be operated independently from a single workstation, enabling simultaneous operation of up to 24 vertical diffusion cells.
Rapid sampling and collection
The Phoenix RDS uses an angled sampling probe designed to simulate manual sampling procedures. During operation, the system automatically withdraws the sample, collects it, and replaces the sampled media volume.
Key sampling capabilities include:
- Rapid sampling in approximately two minutes per cell
- Volumetric accuracy of ±1% or 25 µL
- Staggered sampling with programmable offset times for easier preparation
- Excellent carryover prevention
- Typical rinse volume of approximately 200 µL
- Customizable cleaning protocols using one or multiple solvents and/or air
Samples are collected in 12 × 32 mm vials with pre-slit septa.
Flexible programming
The RDS platform supports extensive programming options to accommodate different diffusion testing requirements. Analysts can configure settings at the individual cell level and modify conditions during an experiment.
Features include:
- Rapid setup of diffusion test parameters
- Configurable operator instructions
- Cell-specific sampling, wash, and rinse settings
- Speed and temperature changes during a run
- Media addition to compensate for evaporation
- Different settings for separate cell groups within the same run
Diffusion Master software and compliance support
Diffusion Master software combines system control, security, and reporting functionality in a single interface. The software also supports compliance workflows including 21 CFR Part 11 requirements.
Software capabilities include:
- Unlimited users and user groups
- Configurable permissions
- Password management options
- Inactivity timeout settings
- Complete audit trail
- Serial number tracking
- Electronic signatures for archived reports
- Event, error, and report logs
- Database searching and filtering
- On-screen test progress and sample alerts
- Network printer output for status and reports
Two RDS systems can be independently controlled from a single workstation.
Phoenix Diffusion Cells
The system is designed for use with Phoenix Diffusion Cells, which provide improved durability, ease of use, and versatility compared with conventional hand-blown vertical diffusion cells.
Phoenix Diffusion Cell features include:
- Dry heat operation without water-jacketing
- Heavy-duty borosilicate glass construction
- Tight dimensional tolerances
- Large-diameter sampling arm opening
- Compatible with standard pipette tips (~300 µL)
This design simplifies sample extraction while reducing operator training requirements and day-to-day handling complexity.
Phoenix RDS supply kit
Each Phoenix RDS system is supplied with:
- 14 evaporation caps
- 14 stoppers
- One 20 mL disposable syringe
- Tweezers
- Dosage mixer
- Stainless steel laboratory spatula
- Bubble inspection mirror
- Plastic O-ring tool
This provides the accessories needed for initial setup and operation.
Specifications
| Weight | 41.7 kg (92 lb) maximum (dry) |
|---|---|
| Dimensions (W × D × H) | 62.9 × 54.0 × 50.8 cm |
| USP <1724> conformance | 200–900 RPM, accurate to ± 10 % of set point |
| Temperature accuracy | ± 1.0 °C |
| Heating block | Programmable from 25 °C to 45 °C |
| Power consumption | Max. 300 W |
| Sample drawer capacity | Up to 108 vials |
