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Teledyne Isco

Combiflash Torrent

One liter per minute flow rates rapidly purify up to 300 grams of sample

Combiflash Torrent

Large-scale flash purification system. CombiFlash Torrent® systems from Teledyne ISCO offer the same ease of use and high reliability as the CombiFlash and RediSep® product lines, now in a large, development-scale platform. It provides rapid purification with one liter per minute flow rates, capable of purifying up to 300 grams of sample. Its 100 psi pumps accurately deliver a reproducible binary gradient. The CombiFlash Torrent system is designed to be flexible for a variety of large-scale purification needs, with various methods of sample introduction and collection.

The trusted RediSep® columns​ communicate with the system to quickly create methods without error through RFID technology. Column information is directly accessed via the RFID tag on each RediSep column for easy recall of methods. Large scale RediSep columns, with quick Luer connections, are available in a broad range of sizes and media types to suit various applications.

Safety

The patented active solvent sensing technology monitors solvent supply and waste levels, enabling true walk-away automation. Pressure and vapor sensors ensure safety by stopping purification if pressure rises or when there’s a leak. Fully grounded tubing ensures safe operation at high flow rates. Optional air purging of the column simplifies disposal after use.

Versatility

Customize your system with a range of sample introduction and fraction handling configurations to suit your specific needs.

Highly Programmable and Easy to Use

ISCO’s PeakTrak software, the industry standard in flash chromatography, offers a powerful yet intuitive interface, allowing you to quickly access and edit all method parameters from a single screen.

Standard features of the large-scale flash purification system 

  • Run up to 1 L/min binary gradient system
  • 100 psi rated
  • Load up to 300 grams in a single purification run
  • Patented solvent and waste level sensing technology
  • Fully-grounded fluid path
  • Easy-to-use PeakTrak® software
  • Accepts RediSep column sizes from 80 g to 3 kg silica
  • RFID column detection
  • Automated six-port valve and large diameter tubing​​​

Related instruments

RediSep Flash Columns

Easy purification and scale-up from milligram to kilogram.

CombiFlash NextGen 300+

The CombiFlash NextGen 300+ comes standard with all options installed. Flow rate range is from 1 to 300 mL/min at operating pressures up to 300 psi (20 bar).

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