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Supercritical Fluid Chromatography system
The ACCQPrep SFC, a Supercritical Fluid Chromatography system, is the only system on the market to offer bulk collection from stacked injections and multi-sample, walk-up, open-bed collection in one unit.
The compact ACCQPrep® SFC simplifies method complexity and ensures successful separations for users of all experience levels. When paired with an optional SFC AutoSampler (2×2 or 4×2), the ACCQPrep SFC offers versatility without limitations. It provides all this in the smallest Prep SFC footprint on the market. Add the mass spectrometer and ELSD option to collect based on mass(es). Then separate out weak UV absorbing compounds with certainty.
Equipped with a powerful pumping system, the ACCQPrep SFC is capable of running up to 200 mL/min from 5 to 70 percent cosolvent composition to help elute more polar compounds. To perform stacked injections without drifting peaks, stability in the CO2 flow and system back-pressure is intelligently controlled via mass-flow feedback and automated back-pressure regulation.
At the core of the ACCQPrep SFC is a patented Gas-Liquid Separator (GLS) that reduces carryover, is low maintenance and is capable of high cosolvent flow. This unique design enables bulk collection into up to eight vessels with the standard fractionation valve, or expanded open-bed fraction collection with the simple addition of a 2×2 or 4×2 SFC AutoSampler for unattended, multi-sample purifications.
Teledyne ISCO’s reputation for intuitive, functional and easy to use purification software is at the heart of the ACCQPrep SFC, with its familiar PeakTrak® interface navigated via a high-resolution, integrated 15” touchscreen. Quickly make on-the-fly gradient and peak collection changes on the main screen. The Method Editor is easily accessible on a single page with a convenient and practical layout of detailed method parameters.
Green Preparative SFC: Chiral or achiral separations in a single, compact solution with the Supercritical Fluid Chromatography system
- Intuitive – PeakTrak® software removes the complexity of method development in SFC (Supercritical Fluid Chromatography)
- Green Chromatography – CO2 is affordable, environmentally friendly and reduces “strong” solvent use by up to 95%
- Ultra Compact – Do more in less space with a smaller footprint than competing systems
Features of the Supercritical Fluid Chromatography system
Powerful, Easy-to-Use PeakTrak® Control
- Intuitive PeakTrak software minimizes the learning curve and enables the user to efficiently complete their purification, save time, and reduce solvent consumption.
- Log in through a network connection and control the separation remotely from your desktop.
Photo Diode Array Detection
- UV and UV-Vis detectors use PDA technology
- Display spectra in real time or post run
- Collect peaks based on purity indicators
Active Solvent and Waste Level Sensing
- Know before you run with predictive solvent needs and patented active solvent/waste monitoring setting up long stacked-injection sequences or multi-sample queues for success.
- Never run a column dry or overfill your waste container. Reproducible, Versatile Sample Introduction
- AutoInjector allows for single, multiple, or stacked injections.
- Pair with SFC AutoSampler to add multisample capability with automated wash sequences and maximum sample injection precision and repeatability.
Pumping System-Flow Control from 50-200 mL/min, designed for columns up to 3 cm
- A robust CO2 pumping system is paired with an advanced mass-flow controller and automated backpressure regulator to provide the flow control required by the dynamic nature of supercritical CO2.
- Liquid co-solvent pump with standard 4-solvent selection valve capable of composition from 5 to 70%.
- Integrated make-up pump for high CO2 composition.
