PurIon

PurIon Mass Spectrometer for Flash and Prep purification

The PurIon™ Mass Spectrometer offers affordable mass-directed fractionation for labs performing flash and prep purifications on Teledyne Labs systems. The PurIon interfaces seamlessly with the CombiFlash® NextGen, CombiFlash® EZ Prep, and ACCQPrep® to instantly verify the identity of target compounds.

Furthermore, the innovative PeakTrak® software offers single point-control, three preset ionization settings, and the flexibility to customize ionization parameters for maximize signal strength.

The Ion Finder utility helps identify fragments and adducts of your compound and optimize detection parameters using directly injected samples before purification. Highly accessible and easy to use, PurIon is ideal for chemists seeking high-quality mass spectral data without the need for specialized training.

Single Quadrupole Mass Analyzer

The PurIon is a compact, single-quadrupole mass analyzer with an atmospheric pressure interface, optimizing chromatography purification. Thus, it delivers highly reliable molecular weight information for target compounds and their adducts, either during purification or through direct-injection analysis beforehand. This is achieved through proton attachment (M+H)+ in positive ion mode and proton removal (M-H)- in negative ion mode.

Versatile and Reliable

Co-eluting peaks isolate easily using mass selectivity based on mass-to-charge ratio (m/z) of the target analyte. With both electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) capabilities, PurIon provides rapid and reliable confirmation of compounds. Suitable for both normal-phase and reverse-phase applications, it delivers consistent performance. Its extended mass range of 10 Da to 2000 Da enables detection of both small and large molecules.

Available mass spectrometer models

“S” Model

The “S” Model has an operation range of 10 to 1,200 Da (m/z). For instance, the unit can be fitted with either an ESI or APCI ion source. These sources can be quickly exchanged to meet different application needs. Unlike the Base Model, the “S” Model automatically switches between positive and negative ionization modes throughout the run.

In addition, a fluid interface module is included with the PurIon Mass Spectrometer to remove miniscule sample from the purification flow stream and redirect this portion to the mass spectrometer for analysis.

“L” Model

The “L” Model has an operation range of 10 to 2,000 Da (m/z). The unit can be fitted with either an ESI or APCI ion source. These sources can be quickly exchanged to suit different application needs. Like the “S” Model, the “L” Model automatically switches between positive and negative ionization modes during a run.

A fluid interface module is included with the PurIon Mass Spectrometer to remove miniscule sample from the purification flow stream and redirect this portion to the mass spectrometer for analysis.

No more TLC plates for flash. Really?

Yes, really, with the Focused Gradient Generator for flash. Read the info here.